Werdnig-Hoffman disease

/ˌhɑfmən dəˌziz/

Definitions of Werdnig-Hoffman disease

1. noun

   autosomal recessive disease in which the degeneration of spinal nerve cells and brain nerve cells leads to atrophy of skeletal muscles and flaccid paralysis; death usually occurs in early childhood
   type of:

   autosomal recessive defect, autosomal recessive disease

   a disease caused by the presence of two recessive mutant genes on an autosome